Product Name :
pan Cytokeratin Recombinant Mouse Monoclonal Antibody [PD00-15]
Predicted band size :
Observed band size :
Synonyms:
pan ck antibody pan-ck antibody panck antibody
Function :
Cytokeratins comprise a diverse group of intermediate filament proteins (IFPs) that are expressed as pairs in both keratinized and non-keratinized epithelial tissue. Cytokeratins play a critical role in differentiation and tissue specialization and function to maintain the overall structural integrity of epithelial cells. Cytokeratins have been found to be useful markers of tissue differentiation which is directly applicable to the characterization of malignant tumors. For example, cytokeratins 10 and 13 are expressed highly in a subset of squamous cell carcinomas while cytokeratin 18 is expressed in a majority of adenocarcinomas and basal cell carcinomas.Price of 1450754-38-7 Since each epithelium contains at least one acidic and one basic keratin, this antibody is used to observe the distribution of keratin-containing cells in normal epithelia and to identify neoplasms derived from such epithelium. Recognizes human cytokeratins 4, 5, 6, 8, 10, 13, and 18.
Antibody Type:
Recombinant Mouse Monoclonal Antibody
Immunogen :
Recognizes human cytokeratins 4, 5, 6, 8, 10, 13, and 18.2,2-Oxybis(ethylamine) site
Species reactivity:
Human
Verify application:
IHC-P, IF-Cell, FC, mIHC
Coupling :
unconjugated
Clone number:
PD00-15
RRID:
AB_3071816
Form :
Liquid
Concentration :
1ug/ul
Storage instructions:
Store at +4℃ after thawing.PMID:33629514 Aliquot store at -20℃. Avoid repeated freeze / thaw cycles.
Storage buffer solution:
PBS (pH7.4), 0.1% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Subtype:
IgG1
Purification method :
Protein A affinity purified.
ELTSA :
Molecular weight :
Positive control :
Human skin tissue, human breast tissue, human small intestine tissue, MCF-7, human pancreatic carcinoma.