Product Name :
SERPINC1 Rabbit Polyclonal Antibody
Predicted band size :
Observed band size :
Synonyms:
ANT3_HUMAN antibody Antithrombin antibody Antithrombin III antibody Antithrombin-III antibody AntithrombinIII antibody AT 3 antibody AT III antibody AT3 antibody AT3D antibody ATIII antibody 展开
Function :
The serine proteinase inhibitors (serpins) compose a superfamily of proteins with a diverse set of functions, including the control of blood coagulation, complement activation, programmed cell death and development.145508-94-7 In stock Serpins are secreted glycoproteins that contain a stretch of peptide that mimics a true substrate for a corresponding serine protease.2-Amino-2-thiazolin-5-one Purity Antithrombin III (ATIII), an extracellular plasma protein, is a crucial serine protease inhibitor that regulates the coagulation cascade in blood.PMID:33733962 The inhibitory activity of ATIII is amplified in the presence of heparin. ATIII inhibits Thrombin and Factors IXa, Xa and XIa. Defects in the gene SERPINC1, which encodes for ATIII, can cause ATIII deficiency, an autosomal dominant disease which is a risk factor for hereditary thrombophilia.
Antibody Type:
Rabbit Polyclonal Antibody
Immunogen :
Recombinant protein within Human SERPINC1 aa 150-370 / 464.
Species reactivity:
Human, Mouse, Rat
Verify application:
WB, IF-Cell, IHC-P, FC
Coupling :
unconjugated
Clone number:
RRID:
AB_3069205
Form :
Liquid
Concentration :
1ug/ul
Storage instructions:
Store at +4℃ after thawing. Aliquot store at -20℃. Avoid repeated freeze / thaw cycles.
Storage buffer solution:
1*PBS (pH7.4), 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.
Subtype:
IgG
Purification method :
Immunogen affinity purified.
ELTSA :
Molecular weight :
53 kDa
Positive control :
HepG2, mouse smooth muscle tissue, mouse lung tissue, H22, rat kidney tissue, human liver tissue, human small intestine tissue.