Product Name :
Strad Rabbit Polyclonal Antibody
Predicted band size :
Observed band size :
Synonyms:
Protein kinase LYK5 antibody Serologically defined breast cancer antigen NY BR 96 antibody STE20 related adapter protein antibody STRAD alpha antibody STRAD antibody
Function :
The protein encoded by this gene contains a STE20-like kinase domain, but lacks several residues that are critical for catalytic activity, so it is termed a ‘pseudokinase’. The protein forms a heterotrimeric complex with serine/threonine kinase 11 (STK11, also known as LKB1) and the scaffolding protein calcium binding protein 39 (CAB39, also known as MO25). The protein activates STK11 leading to the phosphorylation of both proteins and excluding STK11 from the nucleus. The protein is necessary for STK11-induced G1 cell cycle arrest. A mutation in this gene has been shown to result in polyhydramnios, megalencephaly, and symptomatic epilepsy (PMSE) syndrome. Multiple transcript variants encoding different isoforms have been found for this gene. Additional transcript variants have been described but their full-length nature is not known.
Antibody Type:
Rabbit Polyclonal Antibody
Immunogen :
The antiserum was produced against synthesized peptide derived from human STRAD. AA range:11-60
Species reactivity:
Human, Mouse
Verify application:
WB, IHC-P
Coupling :
unconjugated
Clone number:
RRID:
Form :
Liquid
Concentration :
1ug/ul
Storage instructions:
Store at +4℃ after thawing.Price of Mal-PEG3-NHS ester Aliquot store at -20℃ or -80℃.Formula of 4,4′-Dibromo-2,2′-bipyridine Avoid repeated freeze / thaw cycles.PMID:33380168
Storage buffer solution:
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Subtype:
IgG
Purification method :
Immunogen affinity purified.
ELTSA :
Molecular weight :
46 kDa
Positive control :
Lymph node,Mammary tumor,Synovial membrane tissue,Teratocarcinoma,U