Product Name :
3-Chloro-4-fluoroaniline (CAS 367-21-5)
Synonym :
Application :
CAS:
367-21-5
Purity:
Molecular Weight:
145.56
Formula :
C6H5ClFN
Physical state:
Solid
solubility :
Shipping Condition :
Store at 4° C
Melting point:
42-44° C (lit.)
SMILES:
C1=CC(=C(C=C1N)Cl)F
References:
:Metabolism of 3-chloro-4-fluoroaniline in rat using [14C]-radiolabelling, 19F-NMR spectroscopy, HPLC-MS/MS, HPLC-ICPMS and HPLC-NMR. | Duckett, CJ., et al. 2006. Xenobiotica. 36: 59-77. PMID: 16507513Tyrosine Kinase Inhibitors.159858-21-6 site 20.172913-96-1 SMILES Optimization of Substituted Quinazoline and Pyrido[3,4-d]pyrimidine Derivatives as Orally Active, Irreversible Inhibitors of the Epidermal Growth Factor Receptor Family.PMID:33648421 | Smaill, JB., et al. 2016. J Med Chem. 59: 8103-24. PMID: 27491023An improved analytical method, based on HPLC with electrochemical detection, for monitoring exposure to 3-chloro-4-fluoroaniline. | Eadsforth, CV., et al. 1988. J Anal Toxicol. 12: 330-3. PMID: 3244272Tentative identification of gefitinib metabolites in non-small-cell lung cancer patient plasma using ultra-performance liquid chromatography coupled with triple quadrupole time-of-flight mass spectrometry. | Wang, C., et al. 2020. PLoS One. 15: e0236523. PMID: 32702075Deducing the Conformational Properties of a Tyrosine Kinase Inhibitor in Solution by Optical Spectroscopy and Computational Chemistry. | Kabir, ML., et al. 2020. Front Chem. 8: 596. PMID: 32850633[A high-performance liquid chromatography-tandem mass spectrometry method for the quantitative determination of four genotoxic impurities in gefitinib]. | Sun, C., et al. 2019. Se Pu. 37: 1297-1304. PMID: 34213131Biological monitoring of exposure to 3-chloro-4-fluoroaniline by determination of a urinary metabolite and a hemoglobin adduct. | Boogaard, PJ., et al. 1994. Environ Health Perspect. 102 Suppl 6: 23-5. PMID: 7889853